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Year : 2012  |  Volume : 15  |  Issue : 2  |  Page : 231-234

Analgesic nephropathy as a cause of end-stage renal disease in a 55 year-old Nigerian

1 Department of Medicine, Enugu State University Teaching Hospital, Parklane Enugu, Nigeria
2 Department of Medicine, University of Benin Teaching Hospital Benin City, Nigeria
3 Department of Medicine, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria

Correspondence Address:
U H Okafor
Department of Medicine, Enugu State University Teaching Hospital, Parklane Enugu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1119-3077.97335

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Analgesic nephropathy is a subtle but significant cause of chronic renal failure. There is paucity of data on analgesic nephropathy in Nigeria. This case presentation is to highlight the need to have high index of suspicion in patients at risk of developing analgesic nephropathy. In March 2009 a 55-year-old businessman was referred to the renal unit on account of azotemia by the hematologist who had hitherto managed the patient as a case of refractory anemia. The patient had osteoarthritis for over 10 years and was managed with several analgesic drugs over the same period. He was found to have features suggestive of analgesic nephropathy and had end-stage renal disease. He was commenced on appropriate therapy, and he had a live related kidney transplant six months later. Analgesic nephropathy is preventable and morbidity/mortality can be remarkably reduced with appropriate and prompt intervention.

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