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ORIGINAL ARTICLE
Year : 2012  |  Volume : 15  |  Issue : 4  |  Page : 403-407

Adolescent and adult cleft lip and palate, in Ile-Ife, Nigeria


1 Department of Surgery, Obafemi Awolowo University, Ile-Ife, Nigeria
2 Department of Surgery, Irrua Specialist Teaching hospital, Irrua, Nigeria

Date of Acceptance17-Dec-2011
Date of Web Publication12-Dec-2012

Correspondence Address:
A O Oladele
Plastic Surgery Unit, Department of Surgery, P.O. Box 2032, Obafemi Awolowo University, Ile-Ife
Nigeria
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1119-3077.104512

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   Abstract 

Introduction: Congenital cleft lip and palate (CLP) defects usually present in childhood, especially in places with available and affordable care. In Nigeria, their incidence is low but late presentation in Adult life have been reported. This article aims at reviewing adolescent and adult CLP patients in our center, with the advent of free and available care, and to document the patterns and management outcomes of these patients as an addition to existing literature on the subject of adult CLP.
Materials and Methods: A retrospective review of adolescent and adult CLP patients managed from May 2006 to April 2010. Demographic data as well as clinical information were retrieved from the hospital records and include the type of cleft deformity, surgical intervention prior to presentation, the type of surgery performed and postoperative outcomes. Some pertinent clinical photos were also reviewed.
Results: Adolescent and adults constituted 24% of the 137 patients, their age ranged from 13 to 76 years, with a mean, median and modal age of 28, 22 and 20 years respectively. Unilateral cleft of primary palate was commonest with female preponderance. Most never had surgery, others desired revision surgery or secondary procedures. The outcomes were satisfactory in the 37 procedures performed on 33 patients.
Conclusion: A relatively high ratio of adolescent and adult clefts is observed. Most of them have never had surgical intervention. Some had failed surgical intervention prior to presentation. Satisfactory outcomes were achieved despite late intervention but failed initial intervention was associated with poorer outcomes.

Keywords: Adolescents and adult clefts, cleft lip and palate, cleft lip palate Nigeria


How to cite this article:
Oladele A O, Olabanji J K, Awe O O. Adolescent and adult cleft lip and palate, in Ile-Ife, Nigeria. Niger J Clin Pract 2012;15:403-7

How to cite this URL:
Oladele A O, Olabanji J K, Awe O O. Adolescent and adult cleft lip and palate, in Ile-Ife, Nigeria. Niger J Clin Pract [serial online] 2012 [cited 2019 Sep 15];15:403-7. Available from: http://www.njcponline.com/text.asp?2012/15/4/403/104512


   Introduction Top


Cleft lip and palate (CLP) defects usually present in infancy prompted by early stigmatization. [1],[2],[3] With accessible care in western nations, late presentation is usually for uncorrected nose or secondary lip, nose deformity and occlusal defects. [4],[5] However, despite availability of care, late presentation is reported in Nigeria. [6],[7]

The incidence of CLP in general is low [8] and although adult CLP has been reported from other studies in Nigeria, [9],[10],[11],[12],[13] these do not give a complete picture of the prevalence of adult CLP in our country.

The purpose of this article is to review adolescent and adult CLP patients in our center, with the advent of free and available care, and to document the patterns and management outcomes of these patients as an addition to existing literature on the subject of adult CLP.


   Materials and Methods Top


A retrospective review of all adolescent and adult patients that were treated for CLP defects, at the center from May 2006 to April 2010. This period is marked by the introduction of free specialist care for patients and was preceded by mass publicity.

Information retrieved from hospital records includes demographic data, description of cleft type, types of surgeries performed prior to presentation, type of surgical intervention performed in our center, surgical complications if any, and duration of hospital stay and follow-up. These were subjected to simple statistical analysis using the Statistical Package for Social Scientists Software, version 16. Some preoperative, intraoperative and postoperative clinical photographs were also retrieved and are presented.


   Results Top


A total of 137 patients were managed for cleft lip and palate deformity during the period. Adults and adolescents above 13 years of age were 33 (24.1%). Out of these 33 patients, 11 (33.3%) were males and 22 (66.7%) were females. The mean, median and modal ages were 28, 22 and 20 years, respectively. The ages ranged from 13 to 76 years. The age distribution of patients is shown in [Figure 1]. The details of the distribution of various types of cleft by gender are shown in [Table 1].
Figure 1: Age distribution of adolescent and adult cleft patients on bar chart.

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Table 1: Frequency of different types of adolescent and adult clefts by gender

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Two-thirds of the patients had never had surgery. We performed 37 procedures in the 33 patients. The details of those who had surgery performed before presenting and their outcomes are shown in [Table 2]. No pre-surgical orthodontic treatment or alveolar bone grafts were performed. The unilateral cleft lip was repaired by the rotation advancement technique or its variant, the cleft palate defects were closed by the von langenbeck technique or its modifications. Local anesthesia was employed in six patients while general anesthesia with endotracheal intubation was employed in the others.
Table 2: The diagnoses and outcomes of prior surgery in adult cleft patients at presentation

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The procedures performed on the patients are as follows: cleft palate repair in four patients, bilateral lip repair in four patients, lip nose repair in 21 patients, palate fistula repair in three patients, and lip nose revision in five patients. There was no dehiscence in all lip repairs; the two patients who presented with palate fistula were successfully repaired.

Only four of the patients with cleft palate had been repaired out of which two developed palate fistula and one was successfully repaired. The other patient has been lost to follow-up. Primary nasal reconstruction was performed in some patients with lip and nose repair. Open rhinoplasty method was employed in some patients to achieve alar cartilage repositioning. This is as depicted in [Figure 2].
Figure 2: Adult cleft patient who had open rhinoplasty to correct alar cartilage deformity; (a) preoperative photo, (b) intraoperative photo, (c) immediate postoperative photo, (d) late postoperative photo

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Complications recorded are shown in [Table 3]. Facial edema was due to extensive dissection to achieve nasal reconstruction and usually resolved within a few days [Figure 3]. Hypertrophic scar was managed by topical application of silicone gel. One patient had secondary rhinoplasty to correct narrowing of the nostril, following repair of bilateral cleft lip [Figure 4]. Outcome was poorer in those who had a failed earlier attempt at surgery [Figure 5] and [Figure 6]. An elderly patient also had cleft lip repaired [Figure 7].
Figure 3: A 30-year-old patient who had open rhinoplasty (a) preoperative photo, (b) early postoperative photo showing facial edema, (c) full resolution of edema and good outcome 3 months post operatively

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Figure 4: Bilateral cleft lip in a 30-year-old man who had lip repair (a) preoperative photo, (b) postoperative photo showing narrowing of the nostril, (c) early post operative photo after corrective rhinoplasty.

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Figure 5: Poor cosmetic outcome in patient whose earlier attempt at repair of unilateral and bilateral cleft lip, respectively, before presenting to our unit, resulted in dehiscence. (a) preoperative photos (b) post operative photos

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Figure 6: Poor cosmetic outcome in patient whose earlier attempt at repair of unilateral and bilateral cleft lip, respectively, before presenting to our unit, resulted in dehiscence. (a) preoperative photos (b) post operative photos

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Figure 7: Elderly patient who had cleft lip repair. (a) preoperative photo (b) postoperative photo.

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Table 3 : Complications recorded in the patients

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Five patients were treated as day case surgeries while others were admitted for periods which ranged from 3 days to 28 days. The mean duration of admission was 7 days. (Average duration for cleft palate repair was 11 days while that for lip repair was 5 days.) A patient was admitted for 28 days because she required a lip switch operation, in two stages to repair an upper lip midline defect, and stayed in hospital the whole duration of the time pending division and insetting.

Mean duration of follow-up was 10 weeks, with a median and mode of 4 weeks. Initial satisfactory appearances were sometimes followed by late distortions [Figure 2]d.


   Discussion Top


A higher percentage of adult CLP have been reported from places with poor access to cleft care. [9],[14],[15],[16] The 24% of patients presenting with adult CLP compares with that in other areas. [7],[14],[16] Though the incidence of CLP is low, it is thought that underreporting could contribute [11] bearing in mind the challenges with ascertaining these figures. [17],[18] A more accurate incidence of CLP in the general population will be determined by broad-based multicenter studies.

The female: male ratio of 2:1 in this study group may reflect a higher level of body consciousness even in middle aged. That a third of the patients have had previous attempts at surgery may also refute the thinking that all adult patients with CLP were not documented in childhood but suggests a low level of training in surgeons who performed initial intervention but this record was not available for review.

The management of adolescents and adult patients CLP follows the same principles as that of the child [6] but the delay in presentation means that proposed normal time-lines and treatment protocols are individualized. [19],[20]

Pre surgical orthodontic devices were not used in our patients due to costs. We do not perform labial adhesion [21] in our practice as patients may fail to turn up for definitive surgery

Day case surgery for clefts has advantages [22],[23] and was utilized in five of our patients. Adults are better suited [13] as they are more compliant with administration of local anesthesia, heeding postoperative instructions and communicating postoperative complaints. The need for dissection of the alar cartilages for nasal reconstruction necessitated the use of general anesthesia in many of those who only had cleft lip repair.

Most of our patients required admissions because of the need to ensure adequate post operative care and wound healing prior to discharge as many travelled long distances to access care. This accounted for the long average duration of hospital stay.

The primary correction of the nasal deformity is considered a corner stone of adult cleft lip repair as in the child. [16] Adult cleft rhinoplasty is more challenging than in children below 2 years of age due to significant increase in cleft size with age, less elasticity and a more severe deformity of the nasal cartilages. [14],[22] The cleft nasal deformity is preferably corrected by external rhinoplasty approach and the results are usually satisfactory. [4] Although ecchymosis occurs as a complication, it resolves within a few weeks but late deformities may also occur after initial satisfactory correction and may lead patients to request further revision. [24]

In adult palate repair, the adherent non-pliable mucoperiosteal flaps as well as the near-vertical palatal shelves also make the repair more difficult than in children. [19],[22]

Two patients in this review requested lip and nose revision for previous cleft lip repair from other surgeons, while three of our patients did the same. This is not out of place, as up to 80% of patients have been reported to request secondary nose revision surgery following CLP repair. [21] Four patients had failed lip surgery performed before referral to our center with total dehiscence and scarring, and this significantly affects the final cosmetic outcome [Figure 5] and [Figure 6].

Although CLP patients will require medical supervision throughout life, [20] most of our patients are soon lost to follow-up with a mean duration of 10 weeks. Many of the patients with combined CLP have yet to report for palate repair. This makes it difficult to know the true rates of request for revision surgery, and we only assume they are satisfied with outcomes. The combined repair of both cleft lip and cleft palate in one stage has been a proposed possible solution, but this should be chosen judiciously as it is more invasive and results in higher morbidity. [22],[25] Some authors repair the palatal defect before the lip defects to compel a return for the lip surgery, [19] but this may be difficult to justify as it prolongs the stigmatization to which these patients are already subjected and is not recommended.

Because cleft care is in evolution in Nigeria, [26] adult patients are likely to diminish significantly [2],[9] as the level of awareness increases and the availability of affordable cleft care is assured.

We conclude that there was a high proportion of adolescent and adult patients presenting with CLP deformity with the advent of free cleft care as previously reported. [5],[6] This supports the observation of lack of money as the commonest reason for late presentation. [7] A female preponderance of unilateral clefts was noted and many of these patients had never had any form of treatment. The outcome of surgery was adjudged to be satisfactory in the short term but poor follow-up made long-term evaluation difficult. Failed primary intervention in cleft lip repair was associated with poorer cosmetic outcome at repeat surgery.

 
   References Top

1.Theogaraj SD, Joseph LB, Mani M. Statistical analysis of 750 cleft lip and palate patients. Indian J Plast Surg 2007;40:70-4.  Back to cited text no. 1
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5.Sakamoto T, Sueishi K, Miyazaki H, Katada H, Ebihara T, Kosaka T. Clinical statistical investigation of cleft lip and palate patients aged over 18 years at the department of orthodontics, Suidobashi hospital, Tokyo dental college. Bull Tokyo Dent Coll 2008;49:33-9.  Back to cited text no. 5
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21.Mulliken JB, Martinez-Perez D. The principle of rotation advancement for the repair of unilateral cleft lip and nasal deformity: technical variations and analysis of results. Plast Reconstr Surg 1999;104:1247-60.  Back to cited text no. 21
    
22.Morioka D, Yoshimoto S, Udagawa A, Ohkubo F, Yoshikawa A. Primary repair in adult patients with untreated cleft lip cleft palate. Plast Reconstr Surg 2007;120:1981-8.  Back to cited text no. 22
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    Figures

  [Figure 1], [Figure 2], [Figure 3], [Figure 4], [Figure 5], [Figure 6], [Figure 7]
 
 
    Tables

  [Table 1], [Table 2], [Table 3]



 

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