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ORIGINAL ARTICLE
Year : 2014  |  Volume : 17  |  Issue : 6  |  Page : 735-738

Effect of chronic kidney disease on serum resistin level


1 Department of Biochemistry, Calcutta Medical College, Kolkata, India
2 Department of Life Sciences, Tejganj High School, Burdwan, West Bengal, India
3 Department of Pharmacology, Calcutta Medical College, Kolkata, India
4 Department of Physiology, Calcutta Medical College, Kolkata, India
5 Department of General Surgery, Calcutta Medical College, Kolkata, India

Correspondence Address:
S Dan
FE 367, Salt Lake, Kolkata 700 106, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1119-3077.144387

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Background: Chronic Kidney Diseases (CKD) of all etiologies are usually associated with Insulin Resistance (IR). Resistin is also a protein associated with IR. Some studies conducted abroad have shown that resistin level is higher among CKD patients. Objective: To test if serum resistin level is significantly higher in CKD patients compared to normal individuals. Patients and Methods: 96 CKD patients and 97 normal individuals were included in the study. Written informed consent was obtained from every individual. Results: Serum resistin level was higher in CKD patients compared to control subjects. The difference in serum resistin level between two groups was statistically significant. Conclusion: Our study is probably the first study in India comparing serum resistin levels of CKD patients vis-à-vis control subjects. Further cellular research may be needed to explore this relation.


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