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REVIEW ARTICLE
Year : 2018  |  Volume : 21  |  Issue : 4  |  Page : 401-416

The neuroprotection effect of oxygen therapy: A systematic review and meta-analysis


Department of Orthopedics, School of Medicine, Jinling Hospital, Nanjing University, Nanjing, Jiangsu, China

Correspondence Address:
H Xu
Department of Orthopedics, Jinling Hospital, School of Medicine, Nanjing University, No. 305, Zhongshan East Road, Nanjing 210002, Jiangsu
China
Dr. J Zhao
Department of Orthopedics, Jinling Hospital, School of Medicine, Nanjing University, No. 305, Zhongshan East Road, Nanjing 210002, Jiangsu
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/njcp.njcp_315_16

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This study reviews the oxygen therapy (normobaric oxygen [NBO] and hyperbaric oxygen [HBO]) in both stroke and traumatic brain injury (TBI) patients and meta-analyzes the efficacy of two oxygen therapies in different kinds of injuries. In stroke patients, NBO showed significant improvement in reperfusion rate while there is no favorable outcome effect of HBO treatment. In patients with TBI, HBO showed significant improvement of Glasgow outcome scale score and reduction of overall mortality while NBO may play a favorable role in improving brain metabolism.


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