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Year : 2019  |  Volume : 22  |  Issue : 2  |  Page : 227-231

Short-term antibacterial activity and compressive strength of biodentine containing chlorhexidine/cetirimide mixtures

1 Department of Pediatric Dentistry, Faculty of Dentistry, Cukurova University, Adana, Turkey
2 Department of Pediatric Dentistry, Faculty of Dentistry, Karadeniz Technical University, Trabzon, Turkey
3 Department of Pediatric Dentistry, Faculty of Dentistry, Gazi University, Ankara, Turkey
4 Department of Microbiology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey

Correspondence Address:
Dr. C Deveci
Cukurova University Faculty of Dentistry, Department of Pediatric Dentistry, Adana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/njcp.njcp_436_18

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Background and Purpose: Aim is to evaluate the antibacterial activity and physical properties of Biodentine containing chlorhexidine (CHX)/cetrimide (CT) mixtures at 24 h. Materials and Methods: Powder formulations of CHX (2.5%) and CT (2.5%) were added to the powder of Biodentine and served as experimental groups (EXP). Antibacterial free groups were designed as control (CNT). The antibacterial acitivity (AB) (n = 5; for each) of disc-shaped specimens against Streptococcus mutans and Lactobacillius casei and compressive strength (CS) (n = 10; for each) tests used both for groups after 24 h after polymerization. Statistical Analysis Used: Normality of data were tested with the Shapiro–Wilk test. Significant differences were analyzed with the Mann–Whintey U test for both the methods (agar disk diffusion and compressive strength) at a significance level of P < 0.05. Results: Significantly higher antibacterial effects were obtained in EXP groups compared to the CNTs for both bacteria after 24 h, distinctly (P < 0.01). No differences were found between groups regarding the CS values (P > 0.05). Conclusion: Since the incorporation of 5% CHX/CT to the Biodentine exhibited acceptable antibacterial activity without hampering compressive strength values at 24 h, this combination could be a promising alternative for eliminating the residual bacteria for indirect pulp-capping therapies.

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