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CASE REPORT
Year : 2019  |  Volume : 22  |  Issue : 8  |  Page : 1166-1168

Osmotic demyelination syndrome following acute kidney injury with hypernatremia


Department of Medicine, Abubakar Tafawa Balewa University Teaching Hospital, PMB 0117, Bauchi, Bauchi State, Nigeria

Correspondence Address:
Dr. N H Alkali
Department of Medicine, Abubakar Tafawa Balewa University Teaching Hospital, PMB 0117, Bauchi, Bauchi State
Nigeria
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/njcp.njcp_542_18

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Osmotic demyelination syndrome (ODS) is a life-threatening neurological condition often associated with rapid correction of hyponatremia. While ODS is thought to be rare, with prevalence rates of not more than 0.5% in autopsy series, mortality rates are as high as 90% in some studies. Thus, timely diagnosis and life-saving treatment rest on a high index of suspicion among clinicians. In this report, we discuss the case and literature review of a 45-year-old female with sepsis, acute kidney injury, and spontaneous hypernatremia who developed ODS but responded to therapy with high dose steroids, antibiotics, and supportive care.


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