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An evaluation of effects of platelet-rich-fibrin on postoperative morbidities after lower third molar surgery


1 Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Afyon Kocatepe University, 03030 Afyonkarahisar, Turkey
2 Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, İnönü University, Malatya, Turkey
3 Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Bezmialem Vakif University, İstanbul, Turkey
4 Department of Orthodontics, Faculty of Dentistry, İnönü University, Malatya, Turkey

Correspondence Address:
F Asutay,
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Afyon Kocatepe University, 03030 Afyonkarahisar
Turkey
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Source of Support: None, Conflict of Interest: None

Objectives: The aim of the present study was to assess whether the use of platelet-rich fibrin (PRF) decreased the pain, swelling, and trismus levels of postoperative third molar surgery. Materials and Methods: In a double-blinded, split-mouth randomized study, thirty patients (6 male/24 female, mean age 20.32 years) with bilateral symmetric impacted third molars were enrolled in this study to receive surgery. The PRF mass was randomly placed in one of the extraction sockets, whereas the other socket was left without treatment. The outcome variables were pain, maximum mouth opening (trismus), swelling (edema), and the presence of dry socket which were measured using a 10-point visual analog scale, manual calipers, and 3dMD facial imaging system which was used for the 1 st time in the third molar surgery. Results: Statistical analyses revealed that there were no significant differences between the control and study groups regarding postoperative pain, swelling, and trismus (P > 0.05). Conclusion: The results of this study suggest that PRF was not observed to have a positive effect on postoperative discomfort, so even though, PRF is presumed to have positive effects on healing and recovery processes.


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