Nigerian Journal of Clinical Practice

ORIGINAL ARTICLE
Year
: 2007  |  Volume : 10  |  Issue : 3  |  Page : 234--237

Misoprostol use for cervical ripening and induction of labour in a Nigerian teaching hospital


BA Ekele, DC Nnadi, MA Gana, CE Shehu, Y Ahmed, EI Nwobodo 
 Department of Obstetrics and Gynaecology, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

Correspondence Address:
B A Ekele
Department of Obstetrics and Gynaecology, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

CONTEXT: Induction of labor is always a challenge to many an obstetrician more so when the cervix is unfavorable. OBJECTIVES: To determine the efficacy and safety ofmisoprostol in cervical ripening and labour induction. MATERIALS AND METHOD: Aprospective study spanning 2 years and involving 151 patients admitted for cervical ripening and induction of labor at Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria. 50 microgram (mcg) ofmisoprostol was inserted vaginally every 4 hours until cervix became favorable or onset of labor. RESULTS: Main indications for induction of labour were prolonged pregnancy and hypertensive diseases of pregnancy. An average of 2 insertions of 50 mcg tablet was used to achieve cervical ripening in 107 patients (71%) and 80% (120) had spontaneous labor within 10 hours of insertion. The mean insertion-labor interval was 7.86 hours (SD +/- 2.5). The average duration of labour was 9.36 hours (SD +/- 2.9). Vaginal delivery was achieved in 96% of the patients. Uterine hyperstimulation occurred in 9 patients but there was no case of uterine rupture. CONCLUSION: Misoprostol was effective and safe in cervical ripening and induction of labor with a vaginal delivery rate of 96%. It should be an essential drug in obstetric practice especially in low resource settings.


How to cite this article:
Ekele B A, Nnadi D C, Gana M A, Shehu C E, Ahmed Y, Nwobodo E I. Misoprostol use for cervical ripening and induction of labour in a Nigerian teaching hospital.Niger J Clin Pract 2007;10:234-237


How to cite this URL:
Ekele B A, Nnadi D C, Gana M A, Shehu C E, Ahmed Y, Nwobodo E I. Misoprostol use for cervical ripening and induction of labour in a Nigerian teaching hospital. Niger J Clin Pract [serial online] 2007 [cited 2020 Aug 14 ];10:234-237
Available from: http://www.njcponline.com/article.asp?issn=1119-3077;year=2007;volume=10;issue=3;spage=234;epage=237;aulast=Ekele;type=0