| ORIGINAL ARTICLE |
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| Year : 2012 | Volume
: 15
| Issue : 4 | Page : 424-429 |
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Cardiovascular responses to blood transfusion in children with anemic heart failure
WE Sadoh, AE Sadoh, M Okposio
Department of Child Health, University of Benin Teaching Hospital, Benin City, Nigeria
Correspondence Address:
W E Sadoh
Department of Child Health, University of Benin Teaching Hospital, P. M. B. 1111, Benin City
Nigeria
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1119-3077.104517
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Introduction: This study evaluated the cardiovascular responses to blood transfusion in children with anemic heart failure using mostly clinical parameters.
Materials and Methods: Consecutive patients with anemic heart failure presenting to a children's emergency room and requiring blood transfusion were assessed for heart rate (HR), respiratory rate (RR), systolic blood pressure (SBP), liver size, and oxygen saturation (O 2 sat) pre-transfusion, 1-2 h into transfusion (intra-transfusion), immediate post-transfusion, and at late post-transfusion (24 h later).
Results: A total of 75 patients were recruited of which 46 (61.3%) were males. Their mean age was 43.8 ± 40.3 months while their mean PCV at presentation was 15.0 ± 4.5%. There was a significant mean net reduction of 10 beat per minute (bpm) between the pre (139.7 ± 25.2 bpm) and intra-transfusion (129.6 ± 22.0 bpm) HR, P = 0.0004. The mean net reduction of 4 cycles/ min between the pre and intra-transfusion RR was also significant, P = 0.0033. The two parameters declined in values subsequently.
Conclusion: The HR and RR are two easily measurable indices with reduction in HR and RR by 10 bpm and 4 cycles/min, respectively, from pre-transfusion to intra-transfusion observations. |
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