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CASE REPORT
Year : 2020  |  Volume : 23  |  Issue : 4  |  Page : 581-585

Adult-onset still's disease, an unusual cause of severe acute liver injury: A case report


1 Department of Internal Medicine, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey
2 Department of Gastroenterology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey
3 Department of Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey
4 Department of Infectious Diseases, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey
5 Department of Radiology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey

Correspondence Address:
Dr. S C Adiyaman
Department of Internal Medicine, Dokuz Eylul University Faculty of Medicine, Izmir
Turkey
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/njcp.njcp_1_19

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Adult-onset Still's disease is a systemic inflammatory disease that often presents with spiking fever, typical rash, arthritis, and serositis. However, adult-onset-Still's-disease associated liver injury and acute liver failure are rare. Herein, we report a case of acute liver injury in a 23-year-old female patient with adult-onset Still's disease. She presented to the emergency department with a high fever and sore throat. She was then admitted to the department of infectious diseases with a preliminary diagnosis of an atypical respiratory infection. After being treated with antibiotics and antiviral agents, she was discharged. A few days later, she returned to the emergency department with jaundice and was rehospitalized. This time, she was admitted to the department of gastroenterology, where she was diagnosed with adult-onset Still's disease-associated acute liver injury. Eventually, the patient responded to immunosuppressive treatment with significant clinical improvement.


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