Nigerian Journal of Clinical Practice

ORIGINAL ARTICLE
Year
: 2017  |  Volume : 20  |  Issue : 1  |  Page : 31--36

Prevalence and predictors of placental malaria in human immunodeficiency virus-positive women in Nigeria


EO Izuka1, EO Ugwu1, SN Obi1, BC Ozumba1, TU Nwagha2, CE Obiora-Izuka3 
1 Department of Obstetrics and Gynaecology, Faculty of Medical Sciences, College of Medicine, University of Nigeria, Enugu Campus, Enugu; Department of Obstetrics and Gynaecology, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Nigeria
2 Department of Haematology and Immunology, Faculty of Medical Sciences, College of Medicine, University of Nigeria, Enugu Campus, Enugu; Department of Haematology and Immunology, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Nigeria
3 Department of Paediatrics, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Nigeria

Correspondence Address:
Dr. E O Ugwu
Department of Obstetrics and Gynaecology, University of Nigeria Teaching Hospital, P. M. B. 01129, Enugu 400001
Nigeria

Background: Human immunodeficiency virus (HIV)-infected pregnant women have alterations in cellular and humoral immunity that increase the risks to placental malaria infection. Aim: This study aimed at determining the prevalence and predictors of placental malaria among HIV-positive women in Nigeria. Materials and Methods: It was a longitudinal cohort study of pregnant women receiving antenatal care at a tertiary hospital in Nigeria. Peripheral blood sample for packed cell volume estimation and placental blood sample for malaria parasite estimation were collected from each participant at a presentation in labor and upon delivery, respectively. Results: The Prevalence of placenta malaria (68.6%) and anemia (66.7%) in HIV-positive women were significantly higher than the prevalence of placental malaria (35.3%) and anemia (44.1%) in HIV-negative control (P < 0.001 and P = 0.001 respectively). The employment status was the only sociodemographic factor significantly associated with the development of placental malaria in HIV-positive women (odds ratio: 21.60; 95% confidence interval: 7.1–66.2; P< 0.001). Conclusion: The prevalence of placental malaria is very high among HIV-positive women in Nigeria. Scaling up free distribution of insecticide treated nets in the short term and employment opportunities of HIV-positive women, in the long run, may reduce the prevalence of placental malaria in our population.


How to cite this article:
Izuka E O, Ugwu E O, Obi S N, Ozumba B C, Nwagha T U, Obiora-Izuka C E. Prevalence and predictors of placental malaria in human immunodeficiency virus-positive women in Nigeria.Niger J Clin Pract 2017;20:31-36


How to cite this URL:
Izuka E O, Ugwu E O, Obi S N, Ozumba B C, Nwagha T U, Obiora-Izuka C E. Prevalence and predictors of placental malaria in human immunodeficiency virus-positive women in Nigeria. Niger J Clin Pract [serial online] 2017 [cited 2021 Jan 16 ];20:31-36
Available from: https://www.njcponline.com/article.asp?issn=1119-3077;year=2017;volume=20;issue=1;spage=31;epage=36;aulast=Izuka;type=0